Supplementary Figure 3: Lean and obese mouse body weight and patient characteristics. Related to Fig. 3.
From: SWELL1 is a regulator of adipocyte size, insulin signalling and glucose homeostasis
(a) Body weights of lean and obese mice from which mature adipocytes were isolated for patch-clamp recordings in Fig. 3c–h. (b) Relative mRNA expression of SWELL1/LRRC8A and LRRC8B through E assessed by qPCR in mice raised on normal chow (n = 8) compared to HFD (n = 7). (c) Age, Gender and BMI of patients from which visceral adipocytes were isolated for patch-clamp recordings in Fig. 3i–n. BMI: Body mass index. Significance between the indicated groups in a and b were calculated using a two-tailed Student’s t-test. Exact P-values are listed in Supplementary Table 6. Error bars represent mean ± s.e.m.∗(P < 0.05), ∗∗(P < 0.01), ∗∗∗(P < 0.001).
