Supplementary Figure 8: TCGA analysis for Bim and PTEN in breast cancer patients harboring high level of miR93. | Nature Cell Biology

Supplementary Figure 8: TCGA analysis for Bim and PTEN in breast cancer patients harboring high level of miR93.

From: miR-25/93 mediates hypoxia-induced immunosuppression by repressing cGAS

Supplementary Figure 8

(a,b) The levels of Bim and PTEN were not correlated with overall survival of breast cancer patients bearing high level of miR93. Sample number and p value were indicated in the panels. The prognostic significance was assessed by Kaplan–Meier analysis. (c) The expression of MCM7 gene was down-regulated by hypoxia. Knocking down HIF-1α partially rescued MCM7 level in hypoxia. The data is presented as means ± SD (n = 3 independent experiments). Samples were compared using two-tailed Student’s t test. Asterisk indicates P < 0.05.

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