Figure 7: TyrRS activates PI3K signalling in haemocytes. | Nature Communications

Figure 7: TyrRS activates PI3K signalling in haemocytes.

From: Active JNK-dependent secretion of Drosophila Tyrosyl-tRNA synthetase by loser cells recruits haemocytes during cell competition

Figure 7

Haemocytes (red-NimRod) are recruited after secreted TyrRS expression in the dorsal compartment, and PI3K signalling (green-PH_GFP) is activated in these haemocytes. PH-GFP is accumulated in the membranes when PI3K signalling is activated (d–g) compared with the control situation expressing beta-galactosidase (LacZ) (a–c). (a–c,e–g) Magnifications of haemocytes in wing imaginal discs of the third instar larvae. Scale bar, 10 μm. (d) Wing imaginal discs of the third instar larvae expressing secreted TyrRS with recruited haemocytes (white dotted lines). Scale bar, 25 μm. DAPI, 4,6-diamidino-2-phenylindole.

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