Figure 3: Acute neural responses to the positive feedback.
From: Corticostriatal pathways contribute to the natural time course of positive mood

(a) A whole-brain analysis across groups revealed increased activation in bilateral VS as well as in visual occipital areas in response to the positive feedback compared with null feedback at a significance level adjusted such that Type I error was controlled for all voxels in the brain using the false discovery rate (FDR), with q=0.05 in more than 10 contiguous voxels. (b) Mixed ANOVA revealed that both groups responded to the positive feedback with increased VS activation. Bars ±1 s.e.m. *P<0.05. HC, healthy controls (n=25); rMDD, remitted individuals with a history of recurrent MDD (n=25); VS, ventral striatum.