Table 2 The bulk content of representative neurotransmitters and metabolites in the cerebella of Cdc42ep4fl/fl and Cdc42ep4−/− littermate mice.

From: A CDC42EP4/septin-based perisynaptic glial scaffold facilitates glutamate clearance

Neurotransmitters and metabolites (per mg tissue)

 

WT

KO

Glu (nmol)

8.07±0.521

7.97±0.253

Gln (nmol)

5.54±0.459

5.25±0.128

Gly (nmol)

0.66±0.065

0.81±0.13

GABA (nmol)

1.43±0.102

1.48±0.133

L-Ser (nmol)

0.40±0.028

0.40±0.028

D-Ser (nmol)

0.003±0.0001

0.003±0.0000

5-HT (ng)

0.16±0.021

0.16±0.013

5-HIAA (ng)

0.09±0.01

0.11±0.007

NE (ng)

0.35±0.037

0.39±0.013

MHPG (ng)

0.12±0.062

0.07±0.0006

HVA (ng)

0.005±0.003

0.008±0.002

DA (ng)

0.004±0.001

0.005±0.003

DOPAC (ng)

0.006±0.002

0.008±0.004

  1. The amount of glutamate, glutamine and other substances extracted from WT and KO cerebellar tissues (n=3, 3). There was no significant difference. KO, knockout; WT, wild type.
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