Figure 3: ZNF mRNA levels in the monkey MBH at the juvenile-pubertal transition.
From: Epigenetic regulation of puberty via Zinc finger protein-mediated transcriptional repression
During the juvenile–pubertal transition low levels of circulating gonadotropins begin to increase reflecting the reactivation of GnRH pulse generation that triggers puberty in intact monkeys (Fig. 1). All animals were orchidectomized at 16–18 months of age. Because mRNA levels did not change further in LP as compared with EP these two groups were combined before statistical analysis. Vertical bars are means±s.e.m. LJ=late juvenile (n=4–6); EP=early puberty and LP=late puberty (n=5–8; *P<0.05, **P<0.01 and ***P<0.001 versus LJ group; Student’s t-test).
