Figure 5: Genomic distribution of the NSD1+/−-specific CpG sites. | Nature Communications

Figure 5: Genomic distribution of the NSD1+/−-specific CpG sites.

From: NSD1 mutations generate a genome-wide DNA methylation signature

Figure 5

Bar chart representing the percentage distribution of the CpG sites according to genomic annotations extracted from the Illumina 450K array annotation file. We compared the distribution of the CpGs between the data set (424,586 CpGs) and NSD1+/− CpGs (7,085 CpGs) for the regulatory feature group, relation to CpG island and other functional categories such as overlapping enhancer region, DNase hypersensitive sites (DHS) and type of differentially methylated regions (Reprogrammed DMR (RDMR), cancer DMR (cDMR), other DMR) in addition to relation to RefSeq group annotation. The numbers at the top of each bar represent the percentage distribution of CpGs within each category. N refers to north and S refers to south.

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