Figure 6: Adoptive transfer of 1,25D3-treated CD8+ T cells into CD8-deficient recipients prevents goblet cell metaplasia. | Nature Communications

Figure 6: Adoptive transfer of 1,25D3-treated CD8+ T cells into CD8-deficient recipients prevents goblet cell metaplasia.

From: 1,25D3 prevents CD8+Tc2 skewing and asthma development through VDR binding changes to the Cyp11a1 promoter

Figure 6

(a–d) Representative photomicrographs of lung histology (original magnification × 3,200, scale bar, 200 μm). (e) Quantitative analysis of PAS-positive goblet cells was determined in cross-sectional areas of the airway wall. Data (mean+s.e.m.) are from two experiments with three mice per experiment. Linear mixed models were employed; pairwise comparisons were performed using t-tests derived from these models. **P<0.01 these P values remained significant after correction for multiple comparisons; P values that did not reach the threshold P value after adjustment for multiple comparisons (Benjamini–Hochberg58 correction) are shown numerically.

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