Figure 3: Comparison between the predicted and experimentally measured SFVP co-translational folding curves. | Nature Communications

Figure 3: Comparison between the predicted and experimentally measured SFVP co-translational folding curves.

From: Accurate prediction of cellular co-translational folding indicates proteins can switch from post- to co-translational folding

Figure 3

Probabilities of co-translational folding calculated using equation (2) (red triangles) and experimentally measured using pulse-chase labelling7 (open blue squares) for the WT (a) and ΔC mutant (b) of SFVP. Error bars for the experimental results were not reported7, and so error bars were estimated as the average s.d. from the mean from three independent pulse-chase experiments carried out under similar experimental conditions (see Methods section). To match the convention used in the experiment7, the predicted co-translational folding curve was shifted such that the start of the chase is at t=0. WT: R2=0.96, P=0.0001; ΔC mutant: R2=0.99 P=1 × 10−6.

Back to article page