Table 1 Model parameters for SFVP, FRB, HA1 and yeast proteins.

From: Accurate prediction of cellular co-translational folding indicates proteins can switch from post- to co-translational folding

Protein

Total codons encoding protein

Codons encoding co-translational folding domain

Length of observable domain

kF,i (s−1)

kU,i (s−1)

k A,i (AA per second)

SFVP WT

1,257

1–267 (ref. 7)

255 (ref. 62)

0 for i=1–296

20 for i=297–1,257 (ref. 9)

4.34 × 10−5 (ref. 9)

3.9

SFVP ΔC

1,145

1–155 (ref. 7)

143 (ref. 62)*

0 for i=1–184

20 for i=185–1,145 (ref. 9)

4.34 × 10−5 (ref. 9)

3.9 and See Supplementary Table 1

Flag-FRB-GFP

379

11–99 (ref. 25)

99

0 for i=1–128

15.93 for i=129–379(ref. 32)

0.72 (ref. 32)

3.9

HA1

565

53–275 (ref. 53)

222

0 for i=1–304

0.1378 for i=305–565(ref. 32)

7.58 × 10−5 (ref. 32)

3.9

DHOM

359

1–161 (ref. 53)

161

0 for i=1–190

0.0240 for i=191–359 (ref. 32)

2.48 × 10−8 (ref. 32)

See Supplementary Table 1

SBA1

216

1–135 (ref. 66)

135

0 for i=1–164

0.0721 for i=165–216 (ref. 32)

5.40 × 10−6 (ref. 32)

See Supplementary Table 1

EF2

842

570–721 (ref. 53)

151

0 for i=1–750

0.0501 for i=751–842 (ref. 32)

1.03 × 10−7 (ref. 32)

See Supplementary Table 1

DPP3

711

431–671 (ref. 66)

240

0 for i=1–700

0.1811 for i=701–711 (ref. 32)

4.33 × 10−9 (ref. 32)

See Supplementary Table 1

  1. *The last radiolabelled position in SFVP WT is i=255; the length of the observable domain for SFVP ΔC is therefore 143 (=255–112).
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