Figure 1: Motion-based nucleic acid detection.

(a) Hybridization of the target and capture of the Ag nanoparticle-tagged detector probe in a typical sandwich assay on the ternary SH-CP/DTT+MCH surface, including washing of unbound SH-DP-Ag NPs. (b) Dissolution of silver nanoparticle tags in the peroxide fuel, leading to Ag+-enriched fuel. (c) Visual detection of the motion of the catalytic nanowire motors in the resulting Ag+-enriched fuel. C1, C2 and C3 represent hypothetical and increasing target nucleic acid concentrations.