Figure 1: Results of a GWAS for plasma betaine levels in the GeneBank cohort. | Nature Communications

Figure 1: Results of a GWAS for plasma betaine levels in the GeneBank cohort.

From: Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease

Figure 1

The Manhattan plot for plasma betaine levels shows four significantly or suggestively associated loci on chromosomes 1q32.2, 2q34 5q14.1 and 16q24.1. The symbols for the genes closest to the lead SNPs are shown in italics and genome-wide thresholds for significant (P=5.0 × 10−8) and suggestive (P=5.0 × 10−6) association are indicated by the horizontal red and blue lines, respectively. P-values were obtained using linear regression with natural log transformed values and adjustment for age and sex.

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