Figure 2: Regional plots for the loci associated with plasma betaine levels.

The regions shown for chromosomes 5q14.1 (a) and 2q34 (b) are centred on the lead SNP (purple diamond) for each respective locus. The degree of LD (r2) between the lead SNP and other variants in the selected interval is given according the colour-coded legend in the box and genes are indicated in the bottom panel. Rs1047891 was formerly designated as rs7422339.