Table 6 Association of chromosome 2q34 Locus (rs715) with Risk of CAD in the CARDIoGRAM Consortium.

From: Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease

Group

n

Effect allele frequency

OR (95% CI)

P–value

Females

26,905

0.30

0.88 (0.83–0.94)

6.3 × 10 −5

Males

26,772

0.31

1.00 (0.96–1.05)

0.95

Combined

53,667

0.31

0.95 (0.92–0.99)

0.01

  1. CAD, coronary artery disease; CI, confidence interval; OR, odds ratio; SNP, single-nucleotide polymorphism.
  2. Association results are shown for the C allele of rs715. Analyses with all subjects were adjusted for age and sex, whereas sex-stratified analyses were only adjusted for age.
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