Figure 1: Manhattan plot showing the seven loci harbouring genome-wide significant signals influencing serum CK levels in the Icelandic population. | Nature Communications

Figure 1: Manhattan plot showing the seven loci harbouring genome-wide significant signals influencing serum CK levels in the Icelandic population.

From: Common and rare variants associating with serum levels of creatine kinase and lactate dehydrogenase

Figure 1

Variants are plotted by chromosomal position (x axis) and −log10 P values (y axis). P values above 1 × 10−25 are represented. Two loci (CKM and LILRB5) harbour variants with P values below this cutoff (rs11559024: P=1.8 × 10−115; rs12975366: P=6.5 × 10−44 and rs393600: P=1.4 × 10−33). The red line indicates the threshold for genome-wide significance, determined by the number of tests performed (P=0.05/28.3 million=1.8 × 10−9).

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