Table 1 Descriptive characteristics of the MoBa and Generation R study populations.

From: Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns

Variable

Category

MoBa N (%)

Generation R N (%)

Maternal plasma folate (nmol l−1)

Min–max

1.6–53.2

4.1–45.3

 

Mean

11.9

20.3

 

Median

9.1

19.6

 

25–75th percentile

6.2–16.0

13.3–26.4

Log-transformed maternal plasma folate

Min–max

0.48–4.0

1.4–3.8

 

Mean

2.3

2.9

 

Median

2.2

3.0

 

25–75th percentile

1.8–2.8

2.6–3.3

Maternal age (years)

Mean (s.d.)

29.9 (4.3)

31.5 (4.1)

Maternal education level

Less than secondary school

96 (7.5)

14 (1.8)

 

Secondary school completion

415 (32.3)

267 (34.3)

 

Some college or university

566 (44.1)

203 (26.0)

 

4 Years or more of college/university

206 (16.1)

296 (37.9)

 

Missing

6

10

Parity*

0

537 (41.7)

479 (60.7)

 

1

511 (39.6)

240 (30.4)

 

2

179 (13.9)

63 (8.0)

 

3+

62 (4.8)

7 (0.9)

 

Missing

0

1

Maternal smoking during pregnancy

No

1098 (85.2)

541 (75.6)

 

Yes

191 (14.8)

175 (24.5)

 

Missing

0

74

  1. N=1,289 MoBa and N=790 Generation R participants with maternal plasma folate and newborn DNA methylation data. N=1,275 MoBa and N=713 Generation R participants with complete data were included in the adjusted models.
  2. *Parity was categorized as 1 versus 0 in the statistical models for the Generation R study.