Figure 3: Behavioural abnormalities in ARHGAP33 KO mice. | Nature Communications

Figure 3: Behavioural abnormalities in ARHGAP33 KO mice.

From: Emerging roles of ARHGAP33 in intracellular trafficking of TrkB and pathophysiology of neuropsychiatric disorders

Figure 3

(a) Impaired spontaneous alternations of ARHGAP33 KO mice during the Y-maze test (WT, n=14, KO, n=13, F1,25=5.18, P=0.031, one-way ANOVA). *P<0.05. Bars show mean values. (b) Impaired PPI of ARHGAP33 KO mice (each n=13, P=0.046, Friedman test followed by Scheffe tests). *P<0.05. NS, not significant. Bars show median values. (c) Impaired open field habituation of ARHGAP33 KO mice during the openfield habituation test (each n=14, genotype effect, F1,26=5.08, P=0.033, two-way ANOVA with repeated measures; day 3, P=1.3 × 10−4, day 4, P=7.0 × 10−4, Tukey–Kramer post hoc tests). *P<0.05. NS, not significant. Bars show mean values.

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