Table 1 Characteristics at baseline by BB intake.

From: Chronic stress in mice remodels lymph vasculature to promote tumour cell dissemination

Variable

Category

No BB no. (%)

BB no. (%)

P value

Total

 

863 (90.3)

93 (9.7)

 

Age

Median (range)

60 (30–92)

63 (48–80)

<0.01

 

<65

593 (68.7)

50 (53.8)

<0.01

 

65

270 (31.3)

43 (46.2)

 

BMI

<25

459 (59.8)

48 (53.9)

0.10

 

25–30

238 (31.0)

27 (30.3)

 
 

>30

70 (9.1)

14 (15.7)

 

T*

1

387 (46.0)

51 (54.8)

0.23

 

2

340 (40.4)

31 (33.3)

 
 

3

42 (5.0)

4 (4.3)

 
 

4

72 (8.6)

7 (7.5)

 

N*

0

449 (54.4)

51 (56.0)

0.89

 

1

253 (30.7)

26 (28.6)

 
 

2/3

123 (14.9)

14 (15.4)

 

Ki-67

Median (range)

42 (1–95)

38 (4–90)

0.12

 

≤40

408 (49.2)

53 (57.6)

0.12

 

>40

422 (50.8)

39 (42.4)

 

Peritumoural vascular invasion

Absent

650 (75.8)

73 (79.3)

0.39

 

Focal

110 (12.8)

11 (12.0)

 
 

Extensive

98 (11.4)

8 (8.7)

 

Neoadjuvant chemotherapy

No

716 (83.0)

80 (86.0)

0.45

 

Yes

147 (17.0)

13 (14.0)

 

Type of surgery

MAST

206 (23.9)

20 (21.5)

0.61

 

QUAD

657 (76.1)

73 (78.5)

 

Radiotherapy

No

138 (16.0)

12 (12.9)

0.44

 

Yes

725 (84.0)

81 (87.1)

 

ACEI

No use

763 (88.4)

68 (73.1)

<0.01

 

Use

100 (11.6)

25 (26.9)

 

ARB

No use

817 (94.7)

80 (86.0)

<0.01

 

Use

46 (5.3)

13 (14.0)

 

CCB

No use

808 (93.6)

79 (84.9)

<0.01

 

Use

55 (6.4)

14 (15.1)

 

Diuretic

No use

785 (91.0)

60 (64.5)

<0.01

 

Use

78 (9.0)

33 (35.5)

 

Antithrombotics

No use

837 (97.0)

83 (89.2)

<0.01

 

Use

26 (3.0)

10 (10.8)

 

Statins

No use

812 (94.1)

80 (86.0)

<0.01

 

Use

51 (5.9)

13 (14.0)

 
  1. ACEI, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; BMI, body mass index; CCB, calcium channel blocker; MAST, mastectomy; QUAD, quadrantectomy.
  2. *Clinical stage was used for patients undergoing neoadjuvant chemotherapy. Numbers might not sum up to totals due to missing values. P values were obtained using χ2-test or Fisher’s exact test, as appropriate.