Table 3 Comparison of HM binding by variants of FimHL versus FimH·DsG.

From: Catch-bond mechanism of the bacterial adhesin FimH

FimH variant

kon (FimH·DsG)/ kon (FimHL)

koff (FimH·DsG)/ koff (FimHL)

Kd (FimH·DsG)/ Kd (FimHL)

K12

28

110,000

3,300

F18

41

170,000

3,300

  1. HM, n-heptyl α-D-mannoside.
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