Figure 1: Conservation of Pneumocystis genome structure. | Nature Communications

Figure 1: Conservation of Pneumocystis genome structure.

From: Genome analysis of three Pneumocystis species reveals adaptation mechanisms to life exclusively in mammalian hosts

Figure 1

(a) Conserved synteny among three Pneumocystis genomes. Shared syntenic regions are depicted with grey boxes. Scaffold numbers are listed on the x-axis, and red dots indicate the location of msg genes. (b) Genome-wide SNP frequency between the P. jirovecii isolates from the United States (RU7) and Switzerland (SE8)8 with the same scaffold order as in top panel. The region beyond 8 Mb with a high number of SNPs is composed primarily of small scaffolds containing msg genes not assembled into the 20 large scaffolds. Using our genome assembly (RU7) as a reference, we identified a total of 24,902 SNPs, or 1 every 337 bases, between these 2 isolates, which are over-represented in subtelomeric regions where msg genes are found.

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