Figure 9: A model for TOM1L1 invasive activity.
From: TOM1L1 drives membrane delivery of MT1-MMP to promote ERBB2-induced breast cancer cell invasion
ERBB2 indirectly induces TOM1L1 phosphorylation at Ser321 to promote association with TOLLIP in RAB-7/MT1-MMP-positive late endosomes and MT1-MMP trafficking to plasma membrane for cell invasion.
