Figure 4: The palmitoyl–CoA binding site of PatA. | Nature Communications

Figure 4: The palmitoyl–CoA binding site of PatA.

From: Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA

Figure 4

(a–d) Four views of PatA-S-C16CoA crystal structure showing the binding mechanism of S-C16CoA. The palmitoyl moiety is deeply buried into the hydrophobic tunnel, whereas the coenzyme A moiety extends outwards through the side of the main groove. The 2mFo-DFc electron density map countered at 1 σ for the palmitate ligand is shown.

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