Figure 6: The phosphatidylinositol mannosides binding site. | Nature Communications

Figure 6: The phosphatidylinositol mannosides binding site.

From: Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA

Figure 6

(a,b) Two views showing the docking calculations in which PIM2 attaches to the end side of the main groove, close to the hydrophobic tunnel. (c) Close view of the binding site, showing the location of predicted residues involved in PIM2 interaction that have been mutated (H126, E149, R164, H284) along with mutated residues involved in CoA binding (L197 and F182).

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