Figure 7: Structural similarities between PatA and CmGPAT. | Nature Communications

Figure 7: Structural similarities between PatA and CmGPAT.

From: Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA

Figure 7

(a) Structural superposition of PatA and CmGPAT. Secondary structure elements are labelled. The localization of the fatty acid and acceptor binding sites in CmGPAT are indicated. (b,c) The active site of CmGPAT is located into a main groove, with a hydrophobic tunnel running perpendicular and deeply buried into the core of the enzyme. (d) Structural superposition of the proposed acceptor binding site in PatA and CmGPAT, showing donor and acceptor PatA substrates for spatial reference in white colour. (e) Structural superposition of the CoA binding site in PatA and CmGPAT.

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