Table 2 IN solubility was tested in different solvents.

From: Production of unstable proteins through the formation of stable core complexes

IN solubility (mg ml−1)

1 M NaCl 7 mM CHAPS

1 M NaCl

0.5 M NaCl

E. coli

4.0–5.0

0.1–0.5

0.1–0.3

Insect

4.0–5.0

0.1–0.5

0.1–0.3

Mammalian

4.0–5.0

2.0–3.0

2.0–3.0

  1. IN, integrase.
  2. The proteins produced in mammalian cells showed increased solubility compared to the E. coli and insect cell production.