Figure 7: MYO7A suppresses ripoptosome formation. | Nature Communications

Figure 7: MYO7A suppresses ripoptosome formation.

From: The unconventional myosin CRINKLED and its mammalian orthologue MYO7A regulate caspases in their signalling roles

Figure 7

(a) Proximity ligation assay (PLA) between RIPK1 and CASP8 in SKOV3 cells on control treatment (i), 100 nM SM for 5 h or in cells stably expressing CrmA (iii). (b) PLA between RIPK1 and CASP8 in HT1080 cells on treatment with zVAD (i) or TNF/SM/zVAD (ii). (c) PLA between RIPK1 and CASP8 in SWISS-3T3 cells on the indicated treatments. Nuclei are stained with DAPI (4,6-diamidino-2-phenylindole; blue), PLA signals are in green and Phalloidin staining is in red.

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