Figure 1: Functional partitioning for variants within ARBS for PrCa. | Nature Communications

Figure 1: Functional partitioning for variants within ARBS for PrCa.

From: Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation

Figure 1

Bars graphs detailing %SNP heritability estimates from two models of PrCa relevant functional annotations. (a) Joint comparison of variants within 5 kb of tumour-only and normal-only regions in the ARBS in prostate tissue (P=2.1 × 10−19 for difference by Z-test). (b) Estimates from ARBS in prostate tissue (no longer using a 5 kb flank) and ARBS in LNCaP cell lines7 (P=4.4 × 10−7 for difference). The null is labelled by the dashed lines. Error bars show analytical standard error of estimate.

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