Figure 2: Functional partitioning of heritability across six main epigenetic classes. | Nature Communications

Figure 2: Functional partitioning of heritability across six main epigenetic classes.

From: Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation

Figure 2

Each point corresponds to an estimate of % SNP heritability (y axis) from SNPs within a cell-type-specific functional annotation versus annotation size (%SNPs, x axis). Overall, 544 annotations were tested, and red points indicate significant deviations from the null of equal to %SNPs after accounting for all tests. The two most significant annotations in each class are shown with triangle/cross, respectively, and labelled in bottom right (see Supplementary Data for all annotations).

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