Figure 1: Computational prediction of sp-lncRNA regulation in prostate cancer.

(a) The mechanism by which RNAs that are targeted by the same miRNA cross-regulate the expression of each other and the main features of the computational strategy for predicting sp-lncRNA. (b) The computational strategy of predicting lncRNA-mediated sponge regulation of protein-coding driver genes in prostate cancer. (c) A citros plot showing the computationally predicted sp-lncRNA network. The nodes represent individual genes and the edges represent the predicted regulation between sp-lncRNA and the corresponding protein-coding driver gene. FDR, false discovery rate.