Figure 3: The genetic alteration and the expression profile of the predicted sp-lncRNAs.

(a) The scatter plots show the correlation of expression between the predicted sp-lncRNAs and PTEN in both the MSKCC and the Mayo Clinic cohorts. (b) The heat map shows the expression variation of lnc-2, lnc-6 and PTEN across primary and CRPC tumours from the MSKCC cohort. (c) The Turkey boxplot shows the expression distribution of lnc-2 and lnc-6 in tumours with copy number loss and in the tumours without loss. The whiskers correspond to the lowest datum still within 1.5 interquartile range (IQR) of the lower quartile, and the highest datum still within 1.5 IQR of the upper quartile, respectively. Mann–Whitney U-test was performed for the comparison.