Figure 4: CARD9 is required for the development of the inflammatory environment. | Nature Communications

Figure 4: CARD9 is required for the development of the inflammatory environment.

From: Neutrophil-specific deletion of the CARD9 gene expression regulator suppresses autoantibody-induced inflammation in vivo

Figure 4

(a–c) Wild type (WT) or Card9−/− mice were subjected to K/B × N serum-transfer arthritis as described above and the synovial area was flushed on day 4. The cell-free supernatants of the synovial infiltrates were probed using commercial ELISA assays for the indicated chemokines (a), cytokine (b) and the lipid mediator LTB4 (c). Graphs represent mean and s.e.m. from 4–9 (a), 3–5 (b) or 3–4 (c) mice per group from three independent experiments. *P<0.05; NS, statistically not significant (two-way ANOVA); see the text for actual P values.

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