Figure 5: RAPTOR in the mTORC1 complex engages both mTOR molecules.
From: Tor forms a dimer through an N-terminal helical solenoid with a complex topology
Each of the two KmTor–Lst8 heterodimers are uniformly colored and shown as ribbons superimposed on the cryo-EM density for mTORC1 (EMDB-3212). Our topology of Tor implies that the RAPTOR in the mTORC1 complex engages both mTOR molecules through interaction with the spiral of one mTOR and the bridge of the dimer-related mTOR (interface enclosed in the dotted square).
