Table 2 Monitored LC-MS/MS transitions.

From: CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil

Compound/Metabolite

Parent and daughter ions

5-FU

128.8>41.9

FdU

244.9>155.0

FdUMP

324.9>195.0

FUR

260.9>171.0

EdU

250.9>135.8

EdUMP

330.9>195.0

TFT

249.9>179.7

TFTMP

374.9>179.4

Decitabine

227.0>93.8

Decitabine-MP

307.0>195.0

Pyrimethamine*

248.8>176.9

CBK115334*

284.9>188.9

  1. *Analyzed with electrospray ionization in positive mode.
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