Table 1 ITC data for ATP binding to AKe variants at pH 7 and 25 °C

From: Overlap between folding and functional energy landscapes for adenylate kinase conformational change

Protein

K d app (μM)

Δ H °ITC (kJ mol−1)

− T Δ S °ITC (kJ mol−1)

n

WT

51±13

−2.2±0.4

−22±2

1.0±0.07

M1

0.78±0.2

−51±2

16±3

0.93±0.1

M2

0.98±0.3

−110±10

75±11

1.2±0.1

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