Figure 5: Heritability of DNA methylation at sites with significant interaction between age and genetic variance or age and environmental variance. | Nature Communications

Figure 5: Heritability of DNA methylation at sites with significant interaction between age and genetic variance or age and environmental variance.

From: Genetic and environmental influences interact with age and sex in shaping the human methylome

Figure 5

(a) Total variance of DNA methylation, additive genetic variance, unique environmental variance and heritability plotted against age, based on estimates obtained in interaction models on data from 2,603 individuals. (b) Histogram of heritability at age 25 (green) and at age 50 (purple) for 39,455 CpGs with significant interaction between age and genetic variance or between age and unique environmental variance. Dark blue denotes the overlap of green and purple bars.

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