Figure 7: Zyxin is upregulated in human breast cancer.
From: Zyxin-Siah2–Lats2 axis mediates cooperation between Hippo and TGF-β signalling pathways
(a) Expression of Zyxin, Lats2 and Yap in human breast cell lines. (b) Twelve pairs of fresh frozen breast cancer tissues and corresponding tissues were lysed, and cell lysates were immunoblotted with the indicated antibodies. (N, normal tissues; T, tumour tissues). (c) Zyxin protein is upregulated in human breast cancer. Immunohistochemical staining of Zyxin in representative normal breast tissues and breast cancer tissues on the tissue microarrays. Scale bars, 250 μm. (Brown colour indicates positive immune reaction.) Statistical significance was determined by χ2 test. R is the correlation coefficient.
