Figure 1: Expression of TBM transgene. | Nature Communications

Figure 1: Expression of TBM transgene.

From: Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft

Figure 1

(a) Donor pigs with two distinct hTBM transgenes were used. ICAM-TBM and TBM-TBM. (b) Describes the hTBM expression in porcine aortic endothelial cell (PAECs) from donor pig using FACS analyses (i) and immunohistochemistry staining (ii) of pig heart tissue using human anti-porcine CD31 antibody. (c) Demonstrates the TBM molecule expression in heart tissue from the littermates of donor pigs for baboons #910 and #510 (i and ii), human heart section (iii) and wild-type pig heart section (iv). Scale bar, 50 μm.

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