Figure 5: Changes in proteins of the central carbon metabolism.
From: Systems-wide temporal proteomic profiling in glucose-starved Bacillus subtilis
Changes in protein amount for proteins of selected biosynthetic pathways. (a) Members of the purine biosynthetic pathway (PurR; PurB; PurK; PurN; PurH*; PurM;PurD*; PurL*; PurQ*; PurC*; PurF*). (b) Members of the pyrimidine biosynthetic pathway (PyrK; Pyre; PyrC*; PyrF;PyrAA*; PyrD; PyrAB; PyrB). (c) Members of the arginine biosynthetic pathway (ArgC; ArgD; ArgF*; ArgH*;ArgB; CarB; ArgG*; ArgJ*). (d) Members of the leucine/isoleucine biosynthetic pathway (LeuC; LeuD; IlvC; LeuB*;IlvB*; IlvH*; LeuA*). (e) Members of the cysteine biosynthetic pathway (YtiB; YvgQ; CysH; YvgR; CysC; Sat*). (f) Members of the bacillibactin biosynthetic pathway (DhbA*;DhbB*; DhbE*; DhbF*; DhbC*). Log2 ratios are corrected for the first time point. Asterisks indicate proteins that are significantly altered as determined by analysis of variance (P-value<0.01). Error bars indicate s.d. of the biological replicates (n=3). Grey shading: area of maximal s.d. Orange: centroid of all proteins displayed. Blue: possible protease targets.
