Table 2 Data collection, phasing and refinement statistics

From: Polycomb repressive complex 2 structure with inhibitor reveals a mechanism of activation and drug resistance

 

Native (wild type)

Anomalous

Native (Y641N)

Data collection

 Space group

P21

P21

P21

 Cell dimensions

a, b, c (Å)

69.6, 115.0, 153.0

72.7, 120.9, 149.8

71.3, 115.1, 153.94

α, β, γ (°)

90, 102.53, 90

90, 102.9, 90

90, 103.3, 90

 Resolution (Å)

150–2.62

120–3.28

115–2.98

 Rmerge

0.061 (0.306)*

0.109 (0.658)

0.099 (0.58)

 I/σΙ

16.6 (4.3)

14.2 (2.9)

13.0 (2.5)

 Completeness (%)

99.6 (99.9)

97.7 (97.5)

99.7 (99.6)

 Redundancy

3.4 (3.4)

3.3 (3.2)

3.4 (3.5)

Refinement

 Resolution (Å)

150–2.62

 

115–2.99

 Number of reflections

70,801

 

49,142

 Rwork/Rfree

0.191/0.238

 

0.188/0.24

 No. of atoms

Protein

15,460

 

15,467

Ligand

72

 

72

Zn

14

 

14

Water

36

 

0

 B-factors

Protein

56

 

59

Ligand

48

 

45

 R.m.s.d.

Bond lengths (Å)

0.01

 

0.01

Bond angles (°)

1.1

 

1.16

  1. R.m.s.d., root mean square deviation.
  2. A single crystal was used for each data set.
  3. *Highest resolution shell.
Back to article page