Figure 4: Expression of ETV6 in human colorectal cancer cell lines and clinical specimens.
From: Common genetic variation in ETV6 is associated with colorectal cancer susceptibility
(a) The ETV6 mRNA (top) and protein (bottom) expression levels in five colorectal cancer cell lines. (b) The ETV6 mRNA expression levels were estimated in 112 pairs of colorectal cancer tissues (T) and their adjacent normal tissues (N). The P value was calculated using the Wilcoxon matched-pairs signed-rank test. (c) The ETV6 mRNA expression levels were analysed in paired colon tissues from 41 subjects from TCGA data. The P-values were determined using the paired t-test. (d) Semiquantitative analysis of the immunohistochemical staining intensity of 67 cancer tissues and corresponding adjacent normal tissues. (e) Representative immunohistochemical images of ETV6 protein expression in colorectal cancer tissue (left) and normal epithelial tissue (right). Top, × 100 magnification; bottom, × 200 magnification.
