Table 3 Overview of main transcriptome analysis results obtained from the comparison between CEN.PK113-7D and YSBN2 strains.
Batch | Chemostat | ||||||
|---|---|---|---|---|---|---|---|
GO terms | Reporter metabolite | Reporter TF | ORFs | GO term | Reporter metabolite | Reporter TF | ORFs |
Response to pheromone | CBK1, FUS3 | FUS3, FUS1, STE5, MFA1, STE2, AGA2, BAR1, PRM10, FAR1, STE18, SST2, STE4 | Protein catabolism | RPN4 | PIM1, PRE7, VID24, UMP1, RPN6, CDC48, RPT3, RPN9, RAD23, PRB1, RPN11, PRE4, SCL1, RPT6, UFD1, PUP2, ECM29, RPN1, PRE3, UBX6, LAP4, PRE8, PRE5, YDJ1, PUP1, RPT4, RPN8, PRE2, RPN7, SUE1 | ||
Sterol biosynthesis | (R)-Mevalonate, Episterol | MOT3 | ERG28, ERG26, ERG3, HMG1, ERG13, ERG2, CYB5, MVD1 | Amino-acid biosynthesis | Cys, Gly, Asn, Leu | GCN4 | TRP4, SAM2, GLY1, HIS1, ARG5,6, AGX1, MET13, STR3, SER2, ARG3, BAT2, ALT1, PUT1, SAM1, ECM40, LEU4, ARG1, ARG8, LEU9, ASN1 |
Amino-acid transport | Leu, Phe, Ile, Val, Tyr, ALAxt, Asn, GLNxt, Cys, METxt, Trp, Gly,THRxt, PROxt, HISxt | GLN3, GAT1 | BAP3, CAN1, AGP2, BAP2, PUT4, SAM3, DIP5, AGP1, GAP1 | Heterocycle metabolism | URA7, HEM12, TRP4, ARO10, ADE8, SAM2, HEM2, SDT1, ADE5,7, PDC6, MTD1, SAM1, HMX1, ADH6, AAH1, BIO3, ADE2, COX10 | ||
Proteolysis | RPN4 | PIM1, PRE7, VID24, UMP1, PRD1, RPN6, CDC48, RPT3, RPN9, RAD23, RPN11, PRE4, SCL1, RPT6, UFD1, PHB2, PUP2, RPN1, PRE3, UBX6, PRE8, YTA12, PRE5, YDJ1, PUP1, RPT4, RPN8, PRE2, RPN7 | |||||
Trehalose metabolism | α,α′-Trehalose 6-P, α,α-Trehalose | TPS2 | NTH1, TPS2, UGP1, TSL1, PGM2 | Sterol biosynthesis | 5-Diphospho mevalonate | ERG26, ERG25, ERG1, NCP1, ERG7, ERG9, ERG27, ERG6, HMG1, ERG13, ERG5, ERG2, ERG12, ERG8, CYB5, NSG2, ERG24, MVD1, ERG20 | |
Allantoin metabolism | Allantoin | DUR1,2, DAL1, DAL4, DAL2, DAL7, DAL3 | |||||
Cytokinesis | CBK1 | BOI2, DSE1, SCW11, MYO1, DSE2, CTS1, DSE4 | |||||
