Figure 3: TatD-like DNase expression is associated with parasite virulence.
From: The TatD-like DNase of Plasmodium is a virulence factor and a potential malaria vaccine candidate
Quantitative PCR and western blot assays were performed to measure mRNA and protein levels, respectively, of the TatD-like DNase in rodent malarial parasites. In the histograms presented in a,b parasite pathogenicity increased from the left to right, which positively correlated with transcription. Error bars represent the mean ±s.e.m. of three independent experiments. The expression patterns presented in c,d also positively correlated with the transcription results. The top panel indicates the TatD expression in different strains, which were collected at the same stage of the parasites. GAPDH is presented in the bottom panel and was used as a control. The full images of the western blot assays are shown in Supplementary Fig. 13.
