Figure 3: Kaplan–Meier plots of PFS in the fulvestrant and placebo part 1 patients.

(a) PFS of ESR1 mutation (Mut.) status divided by one (red) or greater than one (green) mutation, or WT (blue). (b) PFS by ESR1 mutation AF less than (red) or greater than (green) the median AF. Hazard ratios are relative to WT for both plots. mo, months.