Figure 1: Self-initiated high-throughput home-cage mouse cortical imaging.
From: High-throughput automated home-cage mesoscopic functional imaging of mouse cortex
(a) Mouse cage with auto-head-fixing device and camera for GCaMP6 imaging attached (note RFID reader is underneath the chamber so it is not visible) (b) CAD drawing of auto-head-fixing device showing (partially transparent) fixation tube and tracks in which mouse directs head fixation bar (insets left and right respectively show side and front view of the track). Solenoid-driven pistons for bar fixation and metal plates for contact detection are shown. (c) Close-up photo of auto-head-fixed mouse showing head fixation bar, camera, waterspout and fixation plates. (d) Photo of four mice near the exercise wheel (orange) within home cage with auto-head-fixing device while a fifth mouse is head fixed within the fixation tube at the bottom of the image (only tail is visible).
