Figure 2: Immunohistochemical staining of β-catenin in 52 colorectal cancers. | Nature Communications

Figure 2: Immunohistochemical staining of β-catenin in 52 colorectal cancers.

From: A multigene mutation classification of 468 colorectal cancers reveals a prognostic role for APC

Figure 2

(a) Representative images for APC groups (APCwt, one mutation, two mutations and one mutation plus inferred allelic loss ‘LOH’). Scale bar (bottom right), 20 μm. (b) Allred scores for nuclear (solid bars), cyto (unfilled bars) and membranous (hatched bars) staining of β-catenin in the APC groups: APCwt (n=14), one mutation (n=17), two mutations (n=12) and one mutation plus inferred allelic loss ‘LOH’ (n=9). Error bar represents s.e.m. P=0.014 is for two-tailed, unequal variance Welch t-test. See detailed score information for individual tumours in Supplementary Table 7.

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