Figure 3: Kaplan–Meier survival analysis.
From: A multigene mutation classification of 468 colorectal cancers reveals a prognostic role for APC
(a) MSI tumours by BRAF mutation, (b) MSS tumours by APC groups (APCwt, APC, APC/KRAS, APC/TP53, APC/KRAS/TP53), (c) MSS tumours by the number of truncating mutations (0, 1, 2) in the APC gene, (d) MSS tumours by both APC groups and the number of APC mutations. A−APC, K−KRAS, P−TP53. Five classes: Class 0: APC wild type; Class 1: APC(1), APC(1)/KRAS, APC(1)/TP53; Class 2: APC(2), APC(2)/KRAS, APC(2)/TP53; Class 3: APC(1)/KRAS/TP53; Class 4: APC(2)/KRAS/TP53. A(1) or APC (1) represents one APC mutation and A(2) or APC (2) represents two APC mutations.
