Table 1 Histological scoring system for chronic colitis.

From: Prostaglandin E2 and SOCS1 have a role in intestinal immune tolerance

Histological changes

Score

 

0

1

2

3

Loss of goblet cells

None

Mild/focal

Numerous and diffuse

Numerous and diffuse

Crypt abscesses

None

Few (1 in several sections)

A few (1-4 per section)

Many (≥5 per section)

Hyperaemia in the mucosa

None/not evident

Mild

Diffuse

Diffuse

Cellular infiltration in the lamina propria

None

A few

Moderate/focal

Numerous and diffuse

Elongation of colonic mucosa

Normal (≤100%)

Mild (101–150%)

Evident (≥150%)

Evident (≥150%)

Epithelial erosion

None

Mild/focal

Evident/diffuse

Evident/diffuse

  1. For the assessment of the severity of colitis, histological scores of the proximal, middle and distal portion of the colons were determined, as indicated, and the average was calculated.