Figure 3: Synovial IL-6 expression levels using quantitative PCR.

Intact synovial tissue was processed as described in the Methods and evaluated for IL-6 mRNA transcripts. Note that IL-6 gene expression is higher in RA than OA, and within-disease, higher in hip than knee. *P-values<0.05, calculated by two-tailed unpaired t-test with Welch’s correction (n=13 RA hip, 22 RA knee, 13 OA hip, 15 OA knee). Data presented as mean±s.e.m. (see the Methods for details).