Figure 9: RIPK3 dampens WAT apoptosis and systemic glucose intolerance.
From: The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance

In WT mice, weight gain induced overexpression of RIPK3 in adipocytes that counterbalanced the activation of Caspase-8-dependent apoptosis, thereby dampening WAT inflammation and glucose intolerance.