Figure 2: Similar susceptibility to glutamate neurotoxicity in TrkBc-kit KO and TrkBGFAP KO retinas.
From: Glia- and neuron-specific functions of TrkB signalling during retinal degeneration and regeneration
(a) Immunohistochemical analysis of mouse retinal explants from WT, TrkBc-kit KO and TrkBGFAP KO mice stained with an anti-NeuN antibody. Explants were untreated (control) or treated with 5 mM glutamate for 1 h. Scale bar, 50 μm. (b) Quantification of NeuN-positive cells in the GCL. Data are shown as the mean+s.e.m. (n=6). *P<0.01. GCL, ganglion cell layer; INL, inner nuclear layer.
